Natural genotypes via genetic engineering

Natural genotypes via genetic engineering.

Since livestock were first domesticated, humans have been selecting particular phenotypes as mating stock for each new generation. As a result, humans have been selecting for combinations of alleles that result in animals that better meet our needs: increased production, disease resistance, docility, and so forth. As purpose-bred animals became standard in animal agriculture, breeds began to di...

Genetic engineering compared to natural genetic variations.

By comparing strategies of genetic alterations introduced in genetic engineering with spontaneously occurring genetic variation, we have come to conclude that both processes depend on several distinct and specific molecular mechanisms. These mechanisms can be attributed, with regard to their evolutionary impact, to three different strategies of genetic variation. These are local nucleotide sequ...

Peering into the Natural Genetic Engineering Toolbox

Peering into the Natural Genetic ligate themselves to DNA also mediate the relatively new Engineering Toolbox phenomenon of rolling-circle transposition, as illustrated by the bacterial IS91 element (M Pilar Garcillá n-Barcia et al.). Rolling circle transposition also occurs in Mobile DNA II eukaryotes and is significant because it generates the The amazing and rapidly growing family of rearran...

Plastid genetic engineering via somatic embryogenisis

On Natural Genetic Engineering: Structural Dynamism in Random Boolean Networks

This short paper presents an abstract, tunable model of genomic structural change with in the cell lifecycle and explores its use with simulated evolution. A well-known Boolean model of genetic regulatory networks is extended to include changes in node connectivity based upon the current cell state, e.g., via transposable elements. The underlying behaviour of the resulting dynamical networks is...